Table I.
Association between SATB1 expression and clinicopathological features of 60 hepatocellular carcinoma patients.
| Parameter | Patients, n | Positive SATB1 expression, n (%) | Negative SATB1 expression, n (%) | P-value |
|---|---|---|---|---|
| Gender | 1.000 | |||
| Male | 45 | 30 (66.67) | 15 (33.33) | |
| Female | 15 | 10 (66.67) | 5 (33.33) | |
| Age, years | 0.232 | |||
| ≥55 | 18 | 14 (77.78) | 4 (22.22) | |
| <55 | 42 | 26 (61.90) | 16 (38.10) | |
| Tumor number | 0.839 | |||
| >1 | 17 | 11 (64.71) | 6 (35.29) | |
| 1 | 43 | 29 (67.44) | 14 (32.56) | |
| Tumor size, cm | 0.001 | |||
| ≥5 | 36 | 30 (83.33) | 6 (16.67) | |
| <5 | 24 | 10 (41.67) | 14 (58.33) | |
| Tumor differentiation | 0.000 | |||
| Moderate and poor | 40 | 33 (82.50) | 7 (17.50) | |
| Well | 20 | 7 (35.00) | 13 (65.00) | |
| AFP, ng/ml | 0.449 | |||
| ≥100 | 22 | 16 (72.73) | 6 (27.27) | |
| <100 | 38 | 24 (63.16) | 14 (36.84) | |
| Hemorrhage and/or necrosis | 0.010 | |||
| Present | 26 | 24 (92.31) | 2 (7.69) | |
| Absent | 34 | 16 (47.06) | 18 (52.94) | |
| Invasion and/or metastases | 0.022 | |||
| Present | 19 | 17 (89.47) | 2 (10.53) | |
| Absent | 41 | 23 (56.10) | 18 (43.90) | |
| TNM stage | 0.008 | |||
| I–II | 22 | 7 (31.80) | 15 (68.20) | |
| III–IV | 38 | 33 (86.84) | 5 (13.16) |
SATB1, special AT-rich DNA-binding protein-1; AFP, α-fetoprotein.