Table II.

Clinical features, treatments and responses of 16 infant neuroblastoma cases.

Case no.	Gender	Age, months	Stage	Primary site	Metastatic site	Treatments	Response
1	Male	3	4	Right upper mediastinum	Superior lobe of right lung, pleura, thoracic vertebrae, spinal canal	Surgery + chemotherapy after surgery	CR
2	Male	9	4	Breast neoplasm	Pleural metastasis, lymph node, thoracic vertebrae, spinal canal	Surgery + chemotherapy prior to/after surgery	CR
3	Male	10	4	Posterior mediastinum	Right lung, thoracic cavity	Surgery + chemotherapy after surgery	CR
4	Male	3	4s	Right adrenal gland	Intrahepatic metastasis (diffuse), hemangioma, spleen	Surgery + chemotherapy prior to/after surgery	CR
5	Male	3	4s	Mainly right adrenal gland	Intrahepatic metastasis (diffuse)	Surgery + chemotherapy prior to/after surgery	CR
6	Male	2	4s	Left adrenal gland	Intrahepatic metastasis (diffuse)	Surgery + chemotherapy after surgery	CR
7	Female	1	4s	Right adrenal gland	Intrahepatic metastasis (diffuse)	Surgery + chemotherapy prior to/after surgery	CR
8	Male	11	4	Left retroperitoneal space	Liver, lymph node, skull and left iliac fossa	Surgery + chemotherapy prior to/after surgery + APBSCT	CR
9	Female	11	4s	Left adrenal gland	Left abdominal subcutaneous, lymph node	Surgery + chemotherapy after surgery	CR
10	Male	12	3	Right retroperitoneal space	None	Surgery + chemotherapy after surgery	CR
11	Male	12	4	Left retroperitoneal space	Lumbar vertebrae, spinal neoplasm canal invasion	Surgery + chemotherapy after surgery	PR
12a	Male	5	4s	Left adrenal gland, right retroperitoneal space	Liver, skin, bone, retroperitoneal space	Surgery + chemotherapy after surgery	CR
13	Female	11	4	Neck, mediastinum	Neck lymph node, thoracic vertebrae	Surgery + chemotherapy prior to/after surgery	CR
14	Female	11	3	Front pelvic sacrum	Spinal canal invasion	Surgery + chemotherapy prior to/after surgery	PR
15	Female	11	4	Upper and right retroperitoneal space	Left subclavian lymph node, retroperitoneal space, spinal cord	Surgery + chemotherapy prior to/after surgery + 131I-MIBG APBSCT + radiotherapy	PD
16	Female	4	4s	Right adrenal neoplasm	Intrahepatic metastasis (diffuse)	Surgery + chemotherapy prior to/after surgery	CR

^aFor case 12, liver metastasis was resected after 2 cycles of chemotherapy upon surgery, followed by chemotherapy for 5 cycles. APBSCT, autologous peripheral blood stem cell transplantation; ¹³¹I-MIBG, ¹³¹I-metaiodobenzylguanidine; CR, complete response; PR, partial response; PD, progressive disease.