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. Author manuscript; available in PMC: 2017 Jan 12.
Published in final edited form as: Cell Syst. 2016 Sep 22;3(4):346–360.e4. doi: 10.1016/j.cels.2016.08.011

Figure 5. Subpopulations of Ductal Cells in the Human Pancreas.

Figure 5

(A) Differential expression of MUC1, CFTR, TFF1, and CD44 in PC space defined by the ductal cells. Bottom: moving averages for each gene computed based upon equidistant ranges across PC1.

(B) Heatmaps showing genes that are differentially expressed across PC1 for each of the three donors. Heatmaps including all genes names can be found in Figure S6.

(C) Schematic of the location of terminal and centroacinar ductal cells.

(D) Immunohistochemistry stains of human pancreata for CFTR and MUC1. Note their spatial isolation among the ductal cells.

(E) Differential expression of Muc1, Cftr, Tff2, and Plat in PC space defined by the mouse ductal cells. Bottom: moving averages for each gene computed based upon equidistant ranges across PC1.