Table I.

Clinical and histopathological parameters and miR-199a-5p expression level.

Patient characteristic	No. cases	miR-199a-5p ≤2.24	miR-199a-5p >2.24	χ2 test (P-value)
Total	96
Gender
Male	47	12	35
Female	49	21	28	n.s.
Histological subtype
LS	18	7	11
FS	7	1	6
RMS	7	3	4
LMS	17	9	8
NS	11	4	7
Syn	7	0	7
NOS	22	7	15
Other	7	1	6	n.s.
Tumor size
T1	21	3	18
T2	75	29	46	n.s.
Tumor gradea
I	13	6	7
II	41	9	32
III	42	17	25	n.s.
Tumor stageb
I	10	4	6
II	42	10	32
III	34	12	22
IV	10	6	4	n.s.
Complete resection
Radical (R0)	62	20	42
Not radical (R1)	34	12	22	n.s.
Location
Extremities	61	18	43
Trunk wall	l1	3	8
Head/neck	3	1	2
Abdomen/retro-peritoneum	19	9	10
Multiple locations	2	1	1	n.s.
Number of relapses
0	59	22	37
1	17	5	12
>2	20	5	15	n.s.
Metastasis
Yes	29	10	19
No	67	22	45	n.s.
Patient status
Alive	46	11	35
Succumbed	50	21	29	n.s. (P=0.06)

^aAccording to van Unnik et al, 1993 (50).

^bAccording to the Union for International Cancer Control guidelines (51). LS, liposarcoma; FS, fibrosarcoma; RMS, rhabdomyosarcoma; LMS, leiomyosarcoma; NS, neuronal sarcoma; Syn, synovial sarcoma; NOS, not other specified; tumor size, T1 ≤5 cm in diameter, T2 >5 cm in diameter; n.s., not significant.