Figure 2.

Effect of IL-1β on proliferation of human gallbladder cancer cells in vitro and in vivo. (A) WST-1 assay of GBC-SD cell proliferation changes as a function of IL-1β concentration. (B) WST-1 assay of SGC996 cell proliferation changes as a function of IL-1β concentration. (C) Measurement of tumor volume following tumor injection with or without IL-1β. (D) Measurement of tumor weight following tumor injection with or without IL-1β. Bar graphs present the data obtained from four independent experiments. All data are expressed as the mean ± standard deviation. * P<0.05 compared with the control group and each other. IL, interleukin; WST, water-soluble tetrazolium salts; shRNA, small hairpin RNA.