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Effect of an Akt inhibitor on cell invasiveness and tumor formation in nude mice injected with D1bTgRT cells. (A) Matrigel invasion assay. Each sample was assayed in triplicate, and the bar represents the mean ± SD. ***P=0.0007. The Akt inhibitor was used at a concentration of 25 µM. (B) Tumorigenicity assay. Each sample was assayed in triplicate, and the bar represents the mean ± SD. *P=0.0425. SD, standard deviation.
