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Adiponectin reversed CSE-upregulated expression of TNF-α and IL-8 in 16HBECs. 16HBECs were treated with 5% CSE, 5% CSE + HMW or gAd at different concentrations, and concentrations of (A) TNF-α and (B) IL-8 were detected by ELISA. Each bar represents the mean ± standard deviation from three samples. *P<0.05 vs. 5% CSE (−)/HMW (−)/gAD (−). CSE, cigarette smoke extract; gAd, globular domain; HMW, high molecular weight; IL-8, interleukin-8; TNF-α, tumor necrosis factor-α.
