Figure 3.
LAIR-1 can reduce the proliferation and induce the apoptosis of ME-180 cells. (A) A CCK-8 assay was used to assess the proliferation of L-ME-180, V-ME-180 and ME-180 cells. **P<0.001 vs. L-ME-180 at 72 h. (B) The apoptosis rates of ME-180 cells after LAIR-1 transfection were determined using an annexin V assay. Three independent experiments determined the percentage of the apoptotic rates. *P<0.05. (C) The rate of cell apoptosis was detected using flow cytometry. The results of one experiment show that the difference between L-ME-180 and V-ME-180 (or parental ME-180) was statistically significant. Comparisons were conducted using ANOVA. LAIR-1, leukocyte-associated immunoglobulin-like receptor-1.