Table II.
Cytoplasmic LAIR-1 | Nuclear LAIR-1 | |||||||
---|---|---|---|---|---|---|---|---|
Variable | − (n=15) | + (n=54) | ++ (n=55) | P-value | − (n=61) | + (n=49) | ++ (n=14) | P-value |
Age | 0.756 | 0.780 | ||||||
≤45 | 9 (12.9) | 32 (45.7) | 29 (41.4) | 33 (47.1) | 28 (40.0) | 9 (12.9) | ||
>45 | 6 (11.1) | 22 (40.7) | 26 (48.1) | 28 (51.9) | 21 (38.9) | 5 (9.3) | ||
Tumor size, cm | 0.751 | 0.047 | ||||||
≤4 | 12 (13.5) | 38 (42.7) | 39 (43.8) | 38 (42.7) | 41 (46.1) | 10 (11.2) | ||
>4 | 3 (8.6) | 16 (45.7) | 16 (45.7) | 23 (65.7) | 8 (22.9) | 4 (11.4) | ||
Pathological stage | 0.390 | 0.014 | ||||||
G1 | 0 (0.0) | 3 (42.9) | 4 (57.1) | 1 (14.3) | 3 (42.9) | 3 (42.9) | ||
G2 | 9 (9.4) | 43 (44.8) | 44 (45.8) | 45 (46.9) | 43 (44.8) | 8 (8.3) | ||
G3 | 4 (23.5) | 7 (41.2) | 6 (35.3) | 11 (64.7) | 3 (17.6) | 3 (17.6) | ||
Number of positive lymph nodes | <0.001 | 0.492 | ||||||
0 | 9 (10.7) | 37 (44.0) | 38 (45.2) | 45 (53.6) | 32 (38.1) | 7 (8.3) | ||
≤3 | 0 (0.0) | 7 (36.8) | 12 (63.2) | 9 (47.4) | 7 (36.8) | 3 (15.8) | ||
>3 | 5 (41.7) | 3 (25.0) | 4 (33.3) | 5 (41.7) | 4 (33.3) | 3 (25.0) | ||
T classification | 0.090 | <0.001 | ||||||
T1 | 12 (15.0) | 37 (46.3) | 31 (38.8) | 39 (48.8) | 37 (46.3) | 4 (5.0) | ||
T2 | 3 (8.8) | 14 (41.2) | 17 (50.0) | 21 (61.8) | 9 (26.5) | 4 (11.8) | ||
T3 | 0 (0.0) | 0 (0.0) | 5 (100.0) | 0 (0.0) | 2 (40.0) | 3 (60.0) | ||
N classification | 0.746 | 0.251 | ||||||
N0 | 9 (10.8) | 37 (44.6) | 37 (44.6) | 45 (54.2) | 32 (38.6) | 6 (7.2) | ||
N1 | 6 (15.8) | 16 (42.1) | 16 (42.1) | 16 (42.1) | 16 (42.1) | 6 (15.8) | ||
Clinical stage | 0.914 | 0.027 | ||||||
1 | 6 (12.8) | 22 (46.8) | 19 (40.4) | 24 (51.1) | 22 (46.8) | 1 (2.1) | ||
2 | 3 (9.7) | 13 (41.9) | 15 (48.4) | 20 (64.5) | 8 (25.8) | 3 (9.7) | ||
3 | 6 (14.6) | 16 (39.0) | 19 (46.3) | 16 (39.0) | 17 (41.5) | 8 (19.5) |
LAIR-1, leukocyte-associated immunoglobulin-like receptor-1; -, immunoreactive score (IRS) 0; +, IRS 1–4; ++, IRS 6–12.