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. 2016 Oct 26;12(6):3699–3705. doi: 10.3892/etm.2016.3842

Table II.

Correlation between human cervical cancer clinicopathological features with LAIR-1 expression in subcellular localization.

Cytoplasmic LAIR-1 Nuclear LAIR-1


Variable − (n=15) + (n=54) ++ (n=55) P-value − (n=61) + (n=49) ++ (n=14) P-value
Age 0.756 0.780
  ≤45   9 (12.9) 32 (45.7) 29 (41.4) 33 (47.1) 28 (40.0)   9 (12.9)
  >45   6 (11.1) 22 (40.7) 26 (48.1) 28 (51.9) 21 (38.9)   5 (9.3)
Tumor size, cm 0.751 0.047
  ≤4 12 (13.5) 38 (42.7) 39 (43.8) 38 (42.7) 41 (46.1) 10 (11.2)
  >4   3 (8.6) 16 (45.7) 16 (45.7) 23 (65.7)   8 (22.9) 4 (11.4)
Pathological stage 0.390 0.014
  G1   0 (0.0)   3 (42.9)   4 (57.1) 1 (14.3)   3 (42.9) 3 (42.9)
  G2   9 (9.4) 43 (44.8) 44 (45.8) 45 (46.9) 43 (44.8)   8 (8.3)
  G3   4 (23.5)   7 (41.2)   6 (35.3) 11 (64.7)   3 (17.6)   3 (17.6)
Number of positive lymph nodes <0.001 0.492
  0   9 (10.7) 37 (44.0) 38 (45.2) 45 (53.6) 32 (38.1)   7 (8.3)
  ≤3   0 (0.0)   7 (36.8) 12 (63.2)   9 (47.4)   7 (36.8)   3 (15.8)
  >3   5 (41.7)   3 (25.0)   4 (33.3)   5 (41.7)   4 (33.3)   3 (25.0)
T classification 0.090 <0.001
  T1 12 (15.0) 37 (46.3) 31 (38.8) 39 (48.8) 37 (46.3)   4 (5.0)
  T2   3 (8.8) 14 (41.2) 17 (50.0) 21 (61.8) 9 (26.5)   4 (11.8)
  T3   0 (0.0) 0 (0.0) 5 (100.0) 0 (0.0) 2 (40.0)   3 (60.0)
N classification 0.746 0.251
  N0   9 (10.8) 37 (44.6) 37 (44.6) 45 (54.2) 32 (38.6)   6 (7.2)
  N1   6 (15.8) 16 (42.1) 16 (42.1) 16 (42.1) 16 (42.1)   6 (15.8)
Clinical stage 0.914 0.027
  1   6 (12.8) 22 (46.8) 19 (40.4) 24 (51.1) 22 (46.8)   1 (2.1)
  2   3 (9.7) 13 (41.9) 15 (48.4) 20 (64.5)   8 (25.8)   3 (9.7)
  3 6 (14.6) 16 (39.0) 19 (46.3) 16 (39.0) 17 (41.5)   8 (19.5)

LAIR-1, leukocyte-associated immunoglobulin-like receptor-1; -, immunoreactive score (IRS) 0; +, IRS 1–4; ++, IRS 6–12.