Table 1. Selected candidate target genes and available literature indicating their role in pigmentation and stripe formation in zebrafish.
| Gene | Developmental formation | Adult pigmentationa | Stripe formation | References | ||
|---|---|---|---|---|---|---|
| Melanophore | Iridophore | Xanthophore | ||||
| bnc2 | + | + | + | + | + | Lang et al. (2009) |
| csf1r | + | ? | + | + | + | Parichy & Turner (2003) |
| ece2 | ? | + | ? | + | + | Krauss et al. (2014) |
| ednrb1 | + | + | ? | + | + | Parichy (2006) |
| fbxw4 | + | + | ? | + | + | Kawakami et al. (2000) |
| igsf11 | + | ? | ? | + | + | Eom et al. (2012) |
| kita | + | ? | ? | + | + | Parichy (2006), Mills, Nuckels & Parichy (2007) and Dooley et al. (2013a) |
| kir7.1 | + | − | + | − | + | Iwashita et al. (2006) |
| ltk | ? | + | − | + | + | Fadeev et al. (2015) and Lopes et al. (2008) |
| mitfa | + | ? | − | + | + | Lister, Close & Raible (2001) and Johnson, Nguyen & Lister (2011) |
| mpv17 | ? | + | ? | + | + | Krauss et al. (2013) |
| pmel | + | ? | ? | + | ? | Schonthaler et al. (2005) |
| slc24a5 | + | ? | ? | + | − | Lamason et al. (2005) |
| slc45a2 | ? | ? | ? | + | ? | Dooley et al. (2013b) |
| sox10 | + | ? | ? | ? | + | Dutton et al. (2001) and Elworthy et al. (2003) |
Notes.
a
A role in adult pigmentation mainly indicates the requirement of gene function for survival of different chromatophore lineages or/and pigment formation in adult zebrafish.