Table 5.

Exposure to opioids and sedatives

Parameter	Remifentanil (n = 84)	Fentanyl (n = 37)	Morphine (n = 40)
Opioid
Median duration of opioid infusion, h (range)	47.3 (3.8–120)	35.2 (0.2–120)	40.9 (4.5–120)
Median weighted mean opioid infusion rate: remifentanil and fentanyl, μg kg-1 h-1; morphine, mg kg-1 h-1 (range)	15.4 (3.0–38.2)	3.6 (0.1–7.9)	0.1 (0.0–6.8)
Propofol
Number of patients who received a propofol infusion	76 (90%)	37 (100%)	37 (93%)
Median duration of propofol infusion, h (range)	24.3 (0.0–118)	24.5 (0.0–119.4)	41.7 (0.7–115.3)
Median weighted mean propofol infusion rate, mg kg-1 h-1 (range)	1.93 (0.2–68.8)	2.49 (0.5–11.5)	2.30 (0.3–18.1)
Midazolam
Number of patients who received a midazolam infusion	30 (36%)	11 (30%)	12 (30%)
Median duration of midazolam infusion, h (range)	47.3 (0–117.1)	48.1 (2.3–112.1)	22.4 (1.8–101.4)
Median weighted mean midazolam infusion rate, mg kg-1 h-1 (range)	0.18 (0–17)	0.11 (0–2.3)	0.13 (0.1–0.5)