Table IV.

Details of the survey and testing.

Item	Details
Informed consent	Informed consent was obtained by free will using a written form
Questionnaire on lifestyle	Anamnesis, intake of pharmaceutical products and health food, allergies, smoking, use of skin care products and topical agents, alcohol intake
Inclusion	Included subjects that provided written informed consent, fulfilled the incorporation criteria and did not conflict with the exclusion criteria
Medical interview	Confirmation of the physical conditions and the presence or absence of adverse events
Somatometry	Height (only in the screening test), body weight and body mass index
Physical examination	Systolic and diastolic blood pressure, pulse count
Corneal hydration	Measured on the left forearm, neck and lower eye region
Transepidermal water loss	Measured on the left forearm, neck and lower eye region
Photography of the skin surface	Taken for the left forearm and lower eye region
Evaluation of the skin surface	Examined by a responsible doctor based on the photographs taken as described above
Questionnaire on skin conditions	Subjective recognition of skin conditions
Laboratory examination	Fasting levels of white blood cells, red blood cells, hemoglobin, hematocrit, platelets, total protein, albumin, total billirubin, alkaline phosphatase, aspartate transaminase, alanine transaminase, lactate dehydrogenase, γ-glutamyltranspeptidase, total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low density lipoprotein-cholesterol, urea nitrogen, creatinine, uric acid, Na+, K+, Cl, glucose
Stool examination	Testing of intestinal flora
Log	Status of test article ingestion, physical condition, medicine taking