Table IX.
Position | Group | Screening | Week 4 | Week 8 | Week 12 |
---|---|---|---|---|---|
Forearm | P | 10.3±2.8 | 9.7±3.2 | 9.8±3.8 | 9.8±2.5 |
(−0.5±1.8) | (−0.4±3.5) | (−0.5±2.1) | |||
L | 9.7±1.4 | 10.0±2.0 | 9.1±2.2 | 10.8±2.5a | |
(0.3±1.5) | (−0.6±1.7) | (1.1±1.9c) | |||
H | 10.0±0.8 | 9.5±1.6 | 8.9±1.8a | 10.6±2.3 | |
(−0.5±1.4) | (−1.1±1.6) | (0.6±2.0) | |||
Neck | P | 11.2±5.7 | 11.7±4.6 | 12.0±7.5 | 9.9±3.8 |
(0.4±3.2) | (0.8±5.1) | (−1.4±6.3) | |||
L | 11.4±5.3 | 12.5±7.0 | 9.7±3.9a | 11.4±3.6 | |
(1.1±3.7) | (−1.7±2.9) | (0.0±3.5) | |||
H | 10.4±3.7 | 9.6±2.2 | 9.9±3.5 | 11.0±3.8 | |
(−0.8±2.7) | (−0.5±3.9) | (0.6±3.4) | |||
Lower eye region | P | 24.8±8.2 | 23.2±7.0 | 22.1±6.9 | 21.9±7.1 |
(−1.7±7.1) | (−2.7±6.7) | (−2.9±9.5) | |||
L | 26.4±6.8 | 22.5±4.8b | 22.6±6.5b | 19.9±4.0b | |
(−3.9±4.4) | (−3.8±4.3) | (−6.5±5.5) | |||
H | 24.6±8.5 | 24.6±8.0 | 22.3±3.6 | 24.0±5.6 | |
(0.0±7.1) | (−2.3±7.2) | (−0.5±7.6) |
Each value (g/m2h) represents the mean ± standard deviation, and the difference from the screening value is shown in parenthesis.
P<0.05
P<0.01 by intragroup comparison using paired Student's t-test.
P<0.1 by by intergroup comparison using Dunnett's test using the value of group P as a reference. Group P, placebo group; group L, 25 mg/day heat-killed L. brevis SBC8803 group; group H, 50 mg/day heat-killed L. brevis SBC8803 group; L. brevis, Lactobacillus brevis.