Table 7.
Occurrence of CKI-family members in different vertebrate species
Human | Zebrafish | Fugu | Xenopus tropicalis | Ambystoma mexicanum | |
CDKN1A (p21) | + | -* | + | + | -* |
CDKN1B (p27Kip1) | + | + | + | -† | + |
CDKN1C (p57) | + | + | + | -† | + |
p28Kix1 | - | - | - | +‡ | +‡ |
* Genes most likely present, yet not identified due to limited sequence information; † genes not present in genomic sequence information; ‡ genes so far only present in amphibian species. Databases searched were the human, mouse, rat, fugu, zebrafish and X. tropicalis genome databases, and the EST databases for X. laevis, X. tropicalis, zebrafish, A. mexicanum and A. tigrinum.