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Inhibition of the ependymal CBF by intact wild-type pneumococci (A) or intact pneumolysin-negative pneumococci (B). Ependyma were given 108 CFU/ml (▴), 107 CFU/ml (□), or 106 CFU/ml (•). Each point is the mean ± the standard error of the mean of results from between five and nine independent experiments.
