TABLE 1.
Ependymal ciliary beat frequency during incubation of brain ependymal cilia with antipneumolysin antibodies, pneumolysin plus antipneumolysin antibodies, or pneumolysin alone
| Treatment (no. of expts) | CBF (Hz) (SD)
|
|||
|---|---|---|---|---|
| Baseline reading | 60 min posttreatment | 120 min posttreatment | 180 min posttreatment | |
| Control (6) | 42.2 (3.4) | 44.6 (2) | 36.3 (4.6) | 40.65 (2.9) |
| Pneumolysin at 1 μg/ml (4) | 36.1 (3.5) | 0a | 0a | 0a |
| Antibody PLY-4 (4) | 36.2 (2.8) | 40 (2.3) | 36 (6) | 33.6 (3.7) |
| Antibody PLY-5 (4) | 37.9 (3.5) | 37.5 (4.5) | 38.5 (4) | 39.8 (6.2) |
| Antibody PLY-7 (4) | 39.5 (6.1) | 43 (3) | 41.2 (4) | 42.8 (3.9) |
| Pneumolysin at 1 μg/ml + antibody PLY-4 (6) | 36.3 (3.8) | 40 (3.6) | 36 (3.5) | 33.1 (10.0) |
| Pneumolysin at 1 μg/ml + antibody PLY-5 (6) | 36.0 (4.8) | 36 (4.5) | 35 (5) | 34.9 (7.4) |
| Pneumolysin at 1 μg/ml + antibody PLY-7 (6) | 38.0 (3.5) | 38 (2.6) | 39.8 (2.9) | 40.1 (1.8) |
a
There was total ciliary stasis within 2 min.