TABLE 1.
G. lamblia infections in mast cell-deficient mice
| Groupa | Day postinfection | 104 Parasites (avg ± SD)b |
|---|---|---|
| WBB6F1/J c-kit+/+ | 4 | 5.8 ± 3.3 |
| 10 | 0.3 ± 0.6 | |
| 29 | 0.4 ± 0.7 | |
| 172 | ND | |
| WBB6F1/J c-kitw/wv | 4 | 51.7 ± 26.2c |
| 10 | 98.8 ± 56.7c | |
| 29 | 16.7 ± 18.5c | |
| 172 | 27.9 ± 14.5c |
a
Groups of 4 to 6-week-old female mice were infected with 106 G. lamblia on day 0.
b
Average and standard deviation of the number of parasites found in the small intestines on the indicated day postinfection. Each group consisted of 3 mice per time point. ND, none detected. Data are representative of the results from three separate experiments.
c
P = 0.05 compared to wild-type controls by the Mann-Whitney test.