TABLE 3.
Effect of plasmid content and vlsE complementation on B. burgdorferi infection of C3H/HeN mice at 8 weeks postinfection
| B. burgdorferi B31 clone | Plasmid
|
Shuttle vector
|
No. of 8-wk cultures positive/no. tested for sample site indicated
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| lp25 | lp28-1 | pBSV2 | BBE22 | vlsE | Heart | Bladder | Ear | Joint | Total | |
| 5A4 | + | + | − | − | − | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
| 5A8 | + | − | − | − | − | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 |
| 5A13/pBSV2 | − | − | + | − | − | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 |
| 5A13/pBBE22 | − | + | + | + | − | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
| 5A10/pBBE22:vlsE-2 | − | + | + | + | + | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
| 5A10/pBBE22:vlsE-5 | − | − | + | + | + | 0/6 | 0/6 | 0/6 | 1/6 | 1/6 |