TABLE 1.
Surface accessibility for three anti-NspA MAbs and a panel of Neisseria strainsa
| Strain | Binding index
|
||
|---|---|---|---|
| Me-23 | Me-7 | Me-14 | |
| N. flavescens/pMIDG201nspA | 1 | 73 | 71 |
| N. cinerea/pMIDG201nspA | 1 | 53 | 59 |
| N. subflava/pMIDG201nspA | 1 | 15 | 13 |
| N. flava/pMIDG201nspA | 1 | 42 | 42 |
| N. meningitidis 608B | 1 | 66 | 15 |
All wild-type strains had a binding index of 1 for all three MAbs. The binding index = median fluorescence of samples probed with anti-NspA MAb + fluorescein isothiocyanate-conjugated secondary antibody, divided by the median fluorescence obtained with secondary antibody alone.