. 2004 Nov;72(11):6211–6220. doi: 10.1128/IAI.72.11.6211-6220.2004

TABLE 1.

Effects of opsonization of Pneumocystis prior to inoculation on clearance of organisms from neonatal lungs^a

Treatment group	Log₁₀Pneumocystis nuclei/lungs^b
Uninfected (control)	<3.23, <3.23, <3.23^c
Unopsonized Pneumocystis	5.80, 5.64, 5.82
Immune serum-treated Pneumocystis	5.07, 5.23, 5.18, 5.21^c
MAb 4F11(G1)-treated Pneumocystis	5.89, 5.80, 5.40

Neonatal mice were given i.n. inoculations of PBS or Pneumocystis organisms that were preincubated with polyclonal immune serum or KEX1-specific MAb. The numbers of organisms per lungs were detected microscopically at day 10 postinfection.

Organism burden (expressed as log₁₀ Pneumocystis nuclei per lungs) for individual mice from a single experiment are shown. Note that the limit of detection is 3.23 log₁₀ Pneumocystis nuclei.

P < 0.05 compared to all other groups.