TABLE 1.
Number of infections required before 60% of simulations do not have a fever associated with infection or do not require chemotherapy for the untreated and treated populations, respectively
| No. of var genes in population | Avg interval between infections (days) | No. of infections (time in yrs) required for >60% of simulations to have no fever or require no treatment
|
Increase in time to reach 60% thresholda (-fold) | |
|---|---|---|---|---|
| Untreated | Treated | |||
| 500 | 30 | 21 (1.7) | 45 (3.7) | 2.2 |
| 60 | 19 (3.1) | 36 (5.9) | 1.9 | |
| 1,000 | 30 | 45 (3.7) | 79 (6.5) | 1.8 |
| 60 | 37 (6.1) | 73 (12.0) | 2.0 | |
a
Treated population compared to untreated population.