TABLE 1.
Organ | No. of CD4+ T cells producing cytokine
|
No. of CD8+ T cells producing cytokine
|
||
---|---|---|---|---|
IFN-γ | TNF-α | IFN-γ | TNF-α | |
Spleenb | (3.1 ± 1.7) × 105 | (1.1 ± 5.4) × 105 | (5.8 ± 3.2) × 105 | (6.7 ± 4.0) × 103 |
Liverc | 2.4 × 103 | 6.5 × 102 | 5.0 × 102 | 37 |
Bloodd | 2.6 × 102 | 2.9 × 102 | 70 | 7.3 |
MLNe | (5.6 ± 3.2) × 103 | (1.9 ± 1.4) × 103 | (3.1 ± 2.8) × 104 | (3.8 ± 5.0) × 102 |
Mice were orally immunized ≥15 weeks earlier with Salmonella, and cytokine production was assessed after restimulation with Salmonella lysate. The absolute numbers of cytokine-producing T cells in the indicated organs are shown and are expressed as mean values ± standard deviations.
n = 7.
Cells were pooled from five mice. Values represent an estimate of the total number of cytokine-producing T cells per mouse.
Cells were pooled from four mice. Values represent an estimate of the total number of cytokine-producing T cells per mouse.
Cells were pooled from six mice into three groups. Values represent an estimate of the total number of cytokine-producing T cells per mouse.