Figure 4.

Inhibition of protein synthesis in the BLA or the ENT at the moment of or 3 h after a pure reactivation session does not affect an already consolidated mnemonic trace. Animals implanted with cannulas aimed to the BLA (A) or the entorhinal cortex (B) were trained in the IA task using a 0.5-mA, 2-sec foot-shock and, 24 h later, were submitted to a 20-sec pure reactivation session. Fifteen minutes before (-15 min) or 3 h after (+3 h) that session, the animals received 0.8 μL bilateral infusions of VEH or ANI (80 μg/side). Memory retention was evaluated in a test session carried out 24 h postreactivation (TT2); n = 10 to 12 per group.