Figure 7.

(Top) Four representative Western blots of Egr-1 and actin proteins from the amygdala demonstrating decreased levels of Egr-1 protein following 500 pmole of antisense-ODN. Each column of Egr-1 and actin is protein from the same animal and same lane on the blot. (Bottom) Graphic representation of decrease in Egr-1 protein in the amygdala produced by 250 and 500 pmole of egr-1 antisense-ODN. A statistically significant effect of the antisense-ODN was found (P < 0.003), whereas there was no effect of dose nor an ODN x dose interaction.