Table 2. Incidence rate for anxiety or depression between the tSCI group and other health conditions group.
| Other health conditions group (N = 3,556) | tSCI group (N = 3,556) | IRR (95% CI) | p-value | Adjusted** HR (95% CI) | p-value | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Anxiety/depression | PY | Rate* | Anxiety/depression | PY | Rate* | |||||
| Total | 240 | 10,300.40 | 233.00 | 313 | 10,105.28 | 309.74 | 1.33 (1.12–1.57) | 0.0009 | 1.29 (1.09–1.53) | .0030 |
| Level of SCI | ||||||||||
| ISS <16 | 292 | 9,709.09 | 300.75 | |||||||
| ISS ≥16 | 21 | 396.20 | 530.04 | |||||||
| Age | ||||||||||
| 18–35 | 27 | 2,733.98 | 98.76 | 49 | 2,699.61 | 181.51 | 1.84 (1.15–2.94) | 0.0111 | 1.00 (ref.) | |
| 36–50 | 54 | 2,694.04 | 200.44 | 75 | 2,623.55 | 285.87 | 1.43 (1.01–2.02) | 0.0467 | 1.74 (1.31–2.31) | .0001 |
| 51–65 | 68 | 2,155.77 | 315.43 | 70 | 2,156.93 | 324.54 | 1.03 (0.74–1.44) | 0.8673 | 2.01 (1.51–2.67) | < .0001 |
| 66–80 | 73 | 2,142.83 | 340.67 | 92 | 2,086.51 | 440.93 | 1.29 (0.95–1.76) | 0.0998 | 2.14 (1.60–2.87) | < .0001 |
| >80 | 18 | 573.78 | 313.71 | 27 | 538.70 | 501.21 | 1.60 (0.88–2.90) | 0.1236 | 2.10 (1.42–3.10) | .0002 |
| Sex | ||||||||||
| Male | 76 | 4,833.55 | 157.23 | 121 | 4,729.31 | 255.85 | 1.63 (1.22–2.17) | 0.0009 | 1.00 (ref.) | |
| Female | 164 | 5,466.85 | 299.99 | 192 | 5,375.97 | 357.15 | 1.19 (0.97–1.47) | 0.1010 | 1.48 (1.24–1.76) | < .0001 |
| Economic status | ||||||||||
| <$640 | 138 | 4,884.50 | 282.53 | 184 | 5,044.61 | 364.75 | 1.29 (1.04–1.61) | 0.0233 | 1.93 (1.32–2.81) | .0007 |
| $640–1,280 | 86 | 3,945.46 | 217.97 | 113 | 3,919.38 | 288.31 | 1.32 (0.99–1.75) | 0.0507 | 1.70 (1.16–2.48) | .0062 |
| >$1,280 | 16 | 1,470.45 | 108.81 | 16 | 1,141.30 | 140.19 | 1.29 (0.64–2.58) | 0.4736 | 1.00 (ref.) | |
| Comorbidity | ||||||||||
| HTN | 31 | 970.18 | 319.53 | 36 | 956.63 | 376.32 | 1.18 (0.73–1.90) | 0.5043 | 0.78 (0.58–1.05) | .1058 |
| DM | 7 | 264.47 | 264.69 | 11 | 251.37 | 437.60 | 1.65 (0.64–4.26) | 0.2984 | 0.74 (0.44–1.22) | .2364 |
| CAD | 6 | 144.66 | 414.75 | 9 | 136.76 | 658.09 | 1.59 (0.56–4.46) | 0.3811 | 1.48 (0.86–2.55) | .1625 |
| CCI score | ||||||||||
| 0 | 173 | 8,703.11 | 198.78 | 225 | 8,137.91 | 276.48 | 1.39 (1.14–1.70) | 0.0011 | 1.00 (ref.) | |
| 1 | 41 | 1,041.73 | 393.57 | 54 | 1,152.81 | 468.42 | 1.19 (0.79–1.79) | 0.4006 | 1.58 (1.25–2.01) | .0002 |
| ≥2 | 26 | 555.56 | 468.00 | 34 | 814.56 | 417.40 | 0.89 (0.54–1.49) | 0.6605 | 1.53 (1.14–2.06) | .0048 |
PY, person-year; IRR, incidence rate ratio; CI, confidence interval; HR, hazard ratio; ref., reference; HTN, hypertension; DM, diabetes mellitus; CAD, coronary artery disease; CCI, Charlson Comorbidity Index.
*rate: per 10,000 person-years.
**The hazard ratio were adjusted by age, sex, economic status, comorbidities, and CCI score.