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. 2017 Jan 12;12(1):e0169623. doi: 10.1371/journal.pone.0169623

Table 3. Cox model for the risk of anxiety or depression by the different levels of tSCI compared with other health conditions and tSCI only.

Adjusted* HR (95% CI) p-value Adjusted* HR for tSCI only (95% CI) p-value
Other health conditions 1.00 (ref.)
tSCI group: ISS<16 1.25 (1.06–1.49) .0101 1.00 (ref.)
tSCI group: ISS≥16 2.36 (1.50–3.72) .0002 1.85 (1.17–2.92) .0082
Age
18–35 1.00 (ref.) 1.00 (ref.)
36–50 1.73 (1.30–2.30) .0001 1.57 (1.09–2.25) .0144
51–65 2.01 (1.51–2.68) < .0001 1.61 (1.11–2.33) .0121
66–80 2.17 (1.62–2.91) < .0001 1.99 (1.36–2.90) .0004
>80 2.13 (1.44–3.15) .0001 2.21 (1.34–3.63) .0018
Sex
Male 1.00 (ref.) 1.00 (ref.)
Female 1.51 (1.26–1.80) < .0001 1.36 (1.08–1.73) .0103
Economic status
<$640 1.87 (1.28–2.73) .0012 1.98 (1.17–3.36) .0113
$640–1,280 1.68 (1.15–2.45) .0074 1.79 (1.05–3.03) .0320
>$1,281 1.00 (ref.) 1.00 (ref.)
CCI score
0 1.00 (ref.) 1.00 (ref.)
1 1.59 (1.25–2.01) .0001 1.47 (1.07–2.01) .0177
≥2 1.51 (1.13–2.03) .0060 1.23 (0.83–1.82) .2978
HTN
Yes 0.79 (0.59–1.06) .1165 0.75 (0.50–1.12) .1569
No 1.00 (ref.) 1.00 (ref.)
DM
Yes 0.72 (0.43–1.19) .2012 0.91 (0.47–1.75) .7682
No 1.00 (ref.) 1.00 (ref.)
CAD
Yes 1.49 (0.86–2.57) .1524 1.69 (0.83–3.43) .1492
No 1.00 (ref.) 1.00 (ref.)

* The adjusted HRs were adjusted by age, sex, economic status, comorbidities, and CCI score. CI, confidence interval; ref., reference; HR, hazard ratio; CCI, Charlson Comorbidity Index; HTN, hypertension; DM, diabetes mellitus; CAD, coronary artery disease.