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. 2017 Jan 12;12(1):e0169886. doi: 10.1371/journal.pone.0169886

Fig 3. Effect of nanomaterial (NM) exposure on gene promoter methylation.

Fig 3

Bars connect exposure groups with significant methylation difference, a-d): effects of gold nanoparticles (AuNPs) exposure on promoter methylation levels of Atm (a), Cdk (b), Gp x(c), and Gsr (d) genes in lungs. Effect of single and multi-walled carbon nanotubes (SWCNTs, MWCNTs) exposure on gene promoter methylation levels of Atm (e) gene in lungs. In panels, box plot describes the median (line across the box), inter-quartile range and maximum and minimum values (whiskers). Outliers are shown as colored circles outside the ends of whiskers. Asterisk sign (*) shows significance levels at p = 0.5 (dunn’s statistics). Atm: ataxia telangiectasia mutated; Cdk; cyclin-dependent kinase; Gsr: glutathione reductase; Gpx: glutathione peroxidase.