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Cinobufacin (3.4mg/kg) and bufadienolides (2 mg/kg and 0.5 mg/kg) were evaluated on their influence on tumor volume (A) and nude mice weight (B) of HepG-2 liver tumor model. The drug's influence on relative tumor volume (RTV, shown in C) and relative tumor growth rate (T/C (%), shown in D) of HepG-2 are were also presented. ***: P<0.001 compared to Cinobufacin group.
