Table 4. Effect of bufadienolides on HepG-2 and MKN-45 tumors.
Dosage | Group | HepG-2 | MKN-45 | ||
---|---|---|---|---|---|
Tumor weight(g) | Inhibition(%) | Tumor weight(g) | Inhibition(%) | ||
Blank | 1.565±0.219 | — | 1.038±0.295 | — | |
Cinobufacin | 3.4 ml/kg | 1.143±0.403 | 27.0 | 0.800±0.203 | 23.0 |
Bufadienolides | 2.0 mg/kg | 0.659±0.206*** | 57.9 | 0.696±0.059* | 33.0 |
Bufadienolides | 0.5 mg/kg | 1.109±0.373* | 29.1 | 0.870±0.142 | 16.2 |
***P<0.001.
** P<0.01.
*P<0.05 compared to Cinobufacin group.