Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Novel object recognition deficit of NR1 KD mice is reversed by M1 PAM administration. NR1 KD animals showed no preference for the novel object when treated with vehicle. Pretreatment with VU6004256 resulted in dose-dependent increases in recognition index. Acute treatment with 10 mg/kg VU6004256 in WT animals resulted in an increase in recognition index (n = 8–10/treatment group, * p < 0.05, two-way ANOVA followed by Bonferroni’s post hoc test).
