Figure 4.

[¹⁸F]FDG PET of a patient with dementia.

Severely reduced [¹⁸F]FDG uptake is seen in the parietal lobe (top left) and in the mesial, ventral and lateral cortex of the temporal lobes (top right). Automatic voxel-based analysis of PET images compared with a group of age-matched healthy controls showed a high level of statistical significance (blue areas) of the hypometabolism in the parietal and temporal lobes. Note the presence of small areas of hypometabolism in the left frontal lobe, too. This is the pattern of alterations typically detected in AD.