Genomic locations of Tn917 insertions, excluding siblings, in OG1RF relative to the V583 genome sequence, divided into 10-kb bins. (A) The number of hits throughout the genome. (B) The number of hits in the region immediately surrounding the terminus region. (C) The number of hits throughout the genome excluding the hot-spot region (14.5 to 16.5 Mb). The black box corresponds to the location of the putative V583 pathogenicity island, and the gray box corresponds to the region encoding vancomycin resistance (28), sequences not present in OG1RF.