TABLE 3.
Amino acid substitutions in protease and RT
| Patient | Amino acid substitutionsa
|
|
|---|---|---|
| PR | RT | |
| B | L10I, K14R, L33I, M36I, M46I, I54V, K55R, I62V, L63P, A71V, G73S, V82A, L90M, I93L | V35I, M41L, K43E, S48T, D67DELETED, T69G, K70R, L74I, A98G, L100S, Q102K, K103N, M135I, V179I, M184V, G196E, T215F, K219Q, L227H |
| G | L10I, V11I, T12E, I15V, L19I, R40K, M46L, L63P, A71T, V82A, L90M | D67G, S68G, T69D, K70R, V118I, E122K, I135T, M184V, Q197K, T215F, D218E, K219Q |
| EV | L10V, T12E, G16A, L19I, K20R, L33F, E35D, M36I, M46I, I49V, F53L, I54V, K55R, G57K, D60E, I62V, L63P, A71V, V82A, L90M | M41L, K43E, E44A, T58A, D67E, S68G, L74V, V75M, L100I, Q102N, K104T, V118I, I135T, I142V, T165I, Q174N, Y181I, M184V, L210W, R211K, T215Y, H221Y, V245E |
| ES | L10I, M46L, K55R, I62V, L63P, I72L, G73C, V77I, I85V, L90M | M41L, K43E, E44D, D67N, T69D, L74V, K101E, V118I, E122K, D123E, Y181C, G190S, G196E, E203V, Q207E, L210W, R211K, L214F, T215Y, V245K |
a
Amino acids different from those of the consensus HIVNL4-3.