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. 2004 Nov;78(21):12022–12029. doi: 10.1128/JVI.78.21.12022-12029.2004

TABLE 1.

Correlations between proteins and mRNA species analyzed in this study and expression in different MDR1 genotypes

Species Correlation with the following protein
Expressiona in the following MDR1 genotype:
CXCR4 CCR5 CD4 CC CT TT
P-gp
    Protein r = 0.87b r = −0.22c r = 0.44d 4.2 2.7d 1.35e
    mRNA r = 0.61f NDg ND 1.45 0.97c 0.9c
CXCR4
    Protein r = −0.1h r = −0.28h 19.1 9.1f 5.7f
    mRNA ND ND 1.69 1.23c 0.7f
CCR5
    Protein r = 0.47i 0.25 0.1c 0.12c
    mRNA ND ND ND ND
CD4
    Protein 0.3 0.25c 0.3c
    mRNA ND ND ND
a

In median RFU for protein and arbitrary units relative to GAPDH expression for mRNA.

b

P < 0.0001.

c

P > 0.05.

d

P < 0.05.

e

P < 0.01.

f

P < 0.005.

g

ND, not determined.

h

P > 0.5.

i

P < 0.5.