TABLE 1.
Species | Correlation with the following protein
|
Expressiona in the following MDR1 genotype:
|
||||
---|---|---|---|---|---|---|
CXCR4 | CCR5 | CD4 | CC | CT | TT | |
P-gp | ||||||
Protein | r = 0.87b | r = −0.22c | r = 0.44d | 4.2 | 2.7d | 1.35e |
mRNA | r = 0.61f | NDg | ND | 1.45 | 0.97c | 0.9c |
CXCR4 | ||||||
Protein | r = −0.1h | r = −0.28h | 19.1 | 9.1f | 5.7f | |
mRNA | ND | ND | 1.69 | 1.23c | 0.7f | |
CCR5 | ||||||
Protein | r = 0.47i | 0.25 | 0.1c | 0.12c | ||
mRNA | ND | ND | ND | ND | ||
CD4 | ||||||
Protein | 0.3 | 0.25c | 0.3c | |||
mRNA | ND | ND | ND |
In median RFU for protein and arbitrary units relative to GAPDH expression for mRNA.
P < 0.0001.
P > 0.05.
P < 0.05.
P < 0.01.
P < 0.005.
ND, not determined.
P > 0.5.
P < 0.5.