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. 2004 Nov;78(21):11962–11971. doi: 10.1128/JVI.78.21.11962-11971.2004

FIG. 2.

FIG. 2.

Cells were transfected and analyzed as described in the legend to Fig. 1. (A and B) Results of representative experiments are shown. RLU, relative light units.(A) Inhibition of Zta transactivation by c-Myc is dose dependent. NPC-KT cells were transfected with the indicated amounts of Zta expression plasmid BS(SVp/e)-Zta or Zta control expression plasmid BS(SVp/e) plus either the control c-Myc plasmid pcDNA3 or the c-Myc expression plasmid pcDNA3-c-myc. (B) Inhibition of Zta transactivation of the endogenous Zta-responsive BMRF1 gene in NPC-KT cells. (C) Inhibition of Zta transactivation in the EBV-negative nasopharyngeal cell line CNE1. CNE1 cells were transfected with 2 μg of BS(SVp/e) or BS(SVp/e)-Zta plus 200 ng of pcDNA3 or pcDNA3-c-myc.