FIG. 5.
Anti-α2 monoclonal antibody AK7 inhibits SA11, RRV, and Wa infectivity and SA11 binding in Caco-2 cells. (A) Effect of monoclonal antibodies AK7, W6/32, and control MOPC21 on SA11, RRV, Wa, and CRW-8 infection. For each virus strain, the infectivity titer of virus in MA104 cells treated with test or control monoclonal antibody is expressed as a percentage of the infectivity titer in the absence of monoclonal antibody. (B) AK7 inhibits SA11 binding to Caco-2 cells. The infectious titer of SA11 bound to cells treated with monoclonal antibody is expressed as a percentage of the titer bound in the absence of monoclonal antibody.