Table 10.
Betweenness of promising drug candidates on the validation network.
Rank | Drug name | Betweenness |
---|---|---|
1 | Tamoxifen∗ | 172 |
2 | Paclitaxel∗ | 37 |
3 | Doxorubicin∗ | 32 |
4 | Camptothecin∗∗ | 13 |
5 | Exemestane∗ | 13 |
6 | Fulvestrant∗ | 12 |
7 | Methotrexate∗ | 10 |
8 | Vinblastine∗ | 6 |
9 | Megestrol∗ | 6 |
10 | Aminoglutethimide∗ | 2 |
11 | Letrozole∗ | 2 |
12 | MS-275∗∗ | 2 |
13 | GW-8510∗∗ | 0 |
14 | Phenoxybenzamine∗∗ | 0 |
15 | Tyrphostin_AG-825∗∗ | 0 |
16 | Alsterpaullone∗∗ | 0 |
17 | Celastrol∗∗ | 0 |
∗Known breast cancer drug. ∗∗Potential drug candidate for repositioning.