Table 11.
PageRank of promising drug candidates on the validation network (α = 0.85).
Rank | Drug name | Ranking score |
---|---|---|
1 | Tamoxifen∗ | 0.990 |
2 | Doxorubicin∗ | 0.692 |
3 | Paclitaxel∗ | 0.663 |
4 | Methotrexate∗ | 0.373 |
5 | Fulvestrant∗ | 0.316 |
6 | Camptothecin∗∗ | 0.257 |
7 | Letrozole∗ | 0.252 |
8 | Vinblastine∗ | 0.235 |
9 | Exemestane∗ | 0.176 |
10 | Aminoglutethimide∗ | 0.108 |
11 | Alsterpaullone∗∗ | 0.102 |
12 | Megestrol∗ | 0.101 |
13 | MS-275∗∗ | 0.088 |
14 | Phenoxybenzamine∗∗ | 0.080 |
15 | GW-8510∗∗ | 0.026 |
16 | Celastrol∗∗ | 0.023 |
17 | Tyrphostin_AG-825∗∗ | 0.010 |
∗Known breast cancer drug. ∗∗Potential drug candidate for repositioning.