. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Nov 3;1865(2):186–194. doi: 10.1016/j.bbapap.2016.10.015

Table 1.

Differentially Abundant Islet Proteins by ANOVA Analysis of LC-MS/MS Data

Proteins Detected in TG Islets Only		(gi\| number/gene name)
1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2	gi\|34996495/Rpn2
2	40S ribosomal protein S3	gi\|6755372/Rps3
3	40S ribosomal protein S25	gi\|28372479/Rps25
4	heat shock 70 kDa protein 4	gi\|112293266/Hspa4
5	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	gi\|183396774/Bckdha
6	3-hydroxyacyl-CoA dehydrogenase type-2	gi\|61888838/Hsd17b10
7	guanine nucleotide-binding protein subunit beta-2-like 1	gi\|6680047/Gnb2l1
8	PREDICTED: 60S ribosomal protein L22-like	gi\|309265792/RpL22e
9	aspartyl aminopeptidase isoform b	gi\|161016820/Dnpep
10	serpin I2	gi\|114158681/Spi14

Regulated Islet Proteins		(gi\| number/gene name)	T-Test (P-Value)	Log2(TG/WT)
1	peptidyl-prolyl cis-trans isomerase A	gi\|6679439/Ppia	0.00099	7.7
2	heat shock cognate 71 kDa protein	gi\|31981690/Hspa8	0.0011	9.0
3	60S ribosomal protein L5	gi\|23956082/Rpl5	0.0016	13.1
4	40S ribosomal protein SA	gi\|224994260/Rpsa	0.0021	8.4
5	PREDICTED: 60S ribosomal protein L7 isoform 2	gi\|309270564/Gm5045	0.0044	7.8
6	translationally-controlled tumor protein	gi\|6678437/Tpt1	0.0054	8.7
7	adenylate kinase 2, mitochondrial isoform a	gi\|77020262/Ak2	0.0092	9.3
8	gamma-glutamyltranspeptidase 1	gi\|6679995/Ggt1	0.011	10.8
9	pancreatic triacylglycerol lipase	gi\|37674236/Pnlip	0.019	7.9
10	PREDICTED: 40S ribosomal protein S2-like	gi\|149263154/Gm8841	0.019	8.6
11	heat shock protein HSP 90-beta	gi\|40556608/Hsp90ab1	0.019	9.2
12	isocitrate dehydrogenase [NADP], mitochondrial	gi\|225579033/Idh2	0.022	9.4
13	elongation factor 1-beta	gi\|31980922/Eef1b2	0.024	9.2
14	4F2 cell-surface antigen heavy chain isoform a	gi\|238637277/Slc3a2	0.029	9.1
15	mesencephalic astrocyte-derived neurotrophic factor	gi\|110625813/Manf	0.033	7.9
16	heat shock protein HSP 90-alpha	gi\|6754254/Hsp90aa1	0.033	8.9
17	probable 10-formyltetrahydrofolate dehydrogenase	gi\|283436218/Aldh1l2	0.036	8.4
18	PREDICTED: 60S acidic ribosomal protein P0-like	gi\|94383772/Gm8730	0.037	8.1
19	60S ribosomal protein L10a	gi\|255003735/Rpl10a	0.04	9.0
20	eukaryotic initiation factor 4A-II isoform a	gi\|176865892/Eif4a2	0.051	9.5