Table 3.
Neuropsychological assessment | Region of interest #1
|
Region of interest #2
|
Regression
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|
ROI | Label | MNI coordinates | ROI | Label | MNI coordinates | R2 | t-score | NRME | Covariates | |
Working memory | ||||||||||
Digit Span Sequencing | 85 | Left dorsomedial PFC | (−10, 49.4, 42) | 184 | Right middle occipital | (30, −81.5, 30.8) | 0.482 | −5.64 | 0.015 | None |
Digit Span Sequencing | 144 | Right DMPFC | (9.3, 46.4, 45) | 184 | Right middle occipital | (30, −81.5, 30.8) | 0.459 | −5.35 | 0.025 | None |
Spatial Span Forward | 149 | Right fusiform/parahippocampus | (32.6, −36.5, −14.9) | 180 | Right lateral premotor | (24.3, −4.3, 58.5) | 0.513 | −6.03 | 0.008 | None |
Learning | ||||||||||
BVMT-R, Total Recall | 73 | Left anterior VLPFC | (−25.5, 56.5, 15.6) | 99 | Right SPL | (13.8, −76.1, 45.2) | 0.500 | −5.62 | 0.013 | None |
CVLT, Total 1–5 | 16 | Right frontal eye fields | (23.5, 13.2, 56.5) | 151 | Left rostrolateral PFC | (−26.5, 50.4, 29.6) | 0.508 | −5.93 | 0.017 | None |
Executive function | ||||||||||
D-KEFS Color-Word (Stroop) | 10 | Right superior DLPFC | (39.4, 15.8, 47.7) | 125 | Left sup. ant. insula | (−34.5, 22.4, 10.5) | 0.500 | −5.09 | 0.023 | Education |
D-KEFS Color-Word (Stroop) | 10 | Right superior DLPFC | (39.4, 15.8, 47.7) | 130 | Right superior anterior insula | (34.4, 19.6, 10.1) | 0.404 | −5.13 | 0.017 | None |
D-KEFS Color-Word (Stroop) | 30 | Right post. Inf. parietal | (33.2, −68.6, 44.7) | 136 | Left pre-SMA/dorsal anterior cingulate | (−7.4, 0.2, 48.3) | 0.397 | −5.05 | 0.015 | None |
D-KEFS Color-Word (Stroop) | 30 | Right post. Inf. parietal | (33.2, −68.6, 44.7) | 200 | Right pre-SMA/dorsal cingulate cortex | (5.5, −8.7, 49.9) | 0.517 | −6.42 | 0.009 | None |
D-KEFS Trail Making Test IV | 71 | Right VLPFC | (39.1, 46.7, 6.3) | 116 | Left SPL | (−15.1, −68.2, 52.7) | 0.465 | −5.60 | 0.015 | None |
BVMT-R, Brief Visuospatial Memory Test – Revised; CVLT, California Verbal Learning Test; VLPFC, ventrolateral prefrontal cortex; SPL, superior parietal lobule; PFC, prefrontal cortex.