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. Author manuscript; available in PMC: 2017 Jan 12.
Published in final edited form as: Cell Metab. 2015 Jun 2;21(6):883–890. doi: 10.1016/j.cmet.2015.05.016

Figure 1. During Fasting, AMPK-MKO Mice Have Hypoglycemia, Hyperketosis, and Impaired Breakdown of Muscle.

Figure 1

(A and B) Fatty acid oxidation (A) and blood glucose (B) during fasting (n = 6–12).

(C) Liver and gastrocnemius muscle glycogen (n = 5–6).

(D) ATT after 24 hr fast (n = 6–10).

(E and F) Serum alanine (E, n = 4–5) and serum β-hydroxybutyrate (F, n = 4–6). Data are means ± SEM.

(G) Myofiber CSA change of the TA muscle presented as median ± SEM (n = 4–6). * WT versus AMPK-MKO p < 0.05, **p < 0.01, # fed versus fasted p < 0.05, ## p < 0.01, ### p < 0.001. See also Figure S1 and Table S1.