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. 2017 Jan 10;8(1):84–94. doi: 10.1016/j.stemcr.2016.12.007

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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G. lucidum Polysaccharides Enhance Neurogenesis in Transgenic AD Mice

(A and B) BrdU (red) and NeuN (green) staining of dentate gyrus (DG) sections from mice treated with vehicle (Ctrl, A) and GLP (B).

(C) Quantification of BrdU⁺NeuN⁺ cells from sections as in (A) and (B). n = 9 per group.

(D) Proportion of BrdU⁺NeuN⁺ cells in BrdU⁺ cells (n = 9 per group).

Quantifications are presented as mean ± SEM. ^∗p < 0.05, analyzed by two-tailed t test (C, D) compared with APP/PS1 Ctrl group. Scale bars in (A) and (B), 100 μm; inset is image of high magnification with scale bar representing 10 μm. See also Figure S2.