Table 2.
Regression analyses for demand parameters for the study cigarette at Week 6 and after 24 hours of abstinence.
| Week 6 Study Cigarette | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Intensity | Omax | Pmax | Breakpoint | α | ||||||
| Group | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated increase from the 15.8 mg/g group (95% CI) | p |
| 5.2 | 1.85 (−0.20, 3.90) | 0.08 | 6.78 (2.63, 10.94) | <.01* | 0.12 (−0.07, 0.32) | 0.21 | 0.23 (0.01, 0.44) | 0.04 | 0.00 (−0.02, 0.03) | 0.79 |
| 2.4 | 7.07 (4.96, 9.18) | <.01* | 7.32 (3.42, 11.22) | <.01* | 0.20 (0.01, 0.38) | 0.04 | 0.33 (0.10, 0.55) | 0.01* | 0.02 (−0.01, 0.04) | 0.25 |
| 1.3 | 6.60 (3.51, 9.69) | <.01* | 7.85 (4.00, 11.69) | <.01* | 0.27 (0.11, 0.42) | <.01* | 0.59 (0.30, 0.87) | <.01* | 0.02 (0.00, 0.04) | 0.09 |
| 0.4 | 8.44 (5.55, 11.32) | <.01* | 8.21 (4.27, 12.15) | <.01* | 0.23 (0.05, 0.41) | 0.01 | 0.44 (0.17, 0.71) | <.01* | 0.04 (−0.01, 0.08) | 0.14 |
| 0.4 (HT) | 8.13 (4.12, 12.15) | <.01* | 7.31 (2.96, 11.65) | <.01* | 0.20 (−0.01, 0.40) | 0.06 | 0.37 (−0.01, 0.75) | 0.06 | 0.02 (−0.01, 0.05) | 0.19 |
| 24 Hour Abstinence Study Cigarette | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Intensity | Omax | Pmax | Breakpoint | α | ||||||
| Group | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated reduction from the 15.8 mg/g group (95% CI) | p | Estimated increase from the 15.8 mg/g group (95% CI) | p |
| 5.2 | 2.54 (0.20, 4.88) | 0.03 | 5.12 (1.74, 11.97) | 0.14 | 0.18 (−0.15, 0.52) | 0.28 | 0.43 (0.10, 0.76) | 0.01* | 0.02 (0.00, 0.03) | 0.04 |
| 2.4 | 8.79 (5.77, 11.81) | <.01* | 6.78 (2.08, 11.48) | <.01* | 0.22 (−0.10, 0.54) | 0.17 | 0.56 (0.10, 1.03) | 0.02 | 0.02 (0.00, 0.05) | 0.07 |
| 1.3 | 9.06 (6.24, 11.88) | <.01* | 7.54 (3.49, 11.58) | <.01* | 0.40 (0.12, 0.67) | <.01* | 0.73 (0.42, 1.04) | <.01* | 0.04 (0.02, 0.05) | <.01* |
| 0.4 | 7.86 (5.47, 10.25) | <.01* | 7.02 (2.94, 11.11) | <.01* | 0.28 (0.02, 0.54) | 0.04 | 0.60 (0.23, 0.98) | <.01* | 0.05 (0.03, 0.07) | <.01* |
| 0.4 (HT) | 9.01 (5.67, 12.36) | <.01* | 6.88 (1.10, 12.66) | 0.02 | 0.25 (−0.03, 0.53) | 0.08 | 0.52 (0.06, 0.97) | 0.03 | 0.03 (0.01, 0.05) | <.01* |
An asterisk indicates p<0.0125 for the comparison with the 15.8 mg/g group.