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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Addiction. 2016 Nov 28;112(2):349–359. doi: 10.1111/add.13636

Table 2.

Regression analyses for demand parameters for the study cigarette at Week 6 and after 24 hours of abstinence.

Week 6 Study Cigarette
Intensity Omax Pmax Breakpoint α
Group Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated increase from the 15.8 mg/g group (95% CI) p
5.2 1.85 (−0.20, 3.90) 0.08 6.78 (2.63, 10.94) <.01* 0.12 (−0.07, 0.32) 0.21 0.23 (0.01, 0.44) 0.04 0.00 (−0.02, 0.03) 0.79
2.4 7.07 (4.96, 9.18) <.01* 7.32 (3.42, 11.22) <.01* 0.20 (0.01, 0.38) 0.04 0.33 (0.10, 0.55) 0.01* 0.02 (−0.01, 0.04) 0.25
1.3 6.60 (3.51, 9.69) <.01* 7.85 (4.00, 11.69) <.01* 0.27 (0.11, 0.42) <.01* 0.59 (0.30, 0.87) <.01* 0.02 (0.00, 0.04) 0.09
0.4 8.44 (5.55, 11.32) <.01* 8.21 (4.27, 12.15) <.01* 0.23 (0.05, 0.41) 0.01 0.44 (0.17, 0.71) <.01* 0.04 (−0.01, 0.08) 0.14
0.4 (HT) 8.13 (4.12, 12.15) <.01* 7.31 (2.96, 11.65) <.01* 0.20 (−0.01, 0.40) 0.06 0.37 (−0.01, 0.75) 0.06 0.02 (−0.01, 0.05) 0.19
24 Hour Abstinence Study Cigarette
Intensity Omax Pmax Breakpoint α
Group Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated reduction from the 15.8 mg/g group (95% CI) p Estimated increase from the 15.8 mg/g group (95% CI) p
5.2 2.54 (0.20, 4.88) 0.03 5.12 (1.74, 11.97) 0.14 0.18 (−0.15, 0.52) 0.28 0.43 (0.10, 0.76) 0.01* 0.02 (0.00, 0.03) 0.04
2.4 8.79 (5.77, 11.81) <.01* 6.78 (2.08, 11.48) <.01* 0.22 (−0.10, 0.54) 0.17 0.56 (0.10, 1.03) 0.02 0.02 (0.00, 0.05) 0.07
1.3 9.06 (6.24, 11.88) <.01* 7.54 (3.49, 11.58) <.01* 0.40 (0.12, 0.67) <.01* 0.73 (0.42, 1.04) <.01* 0.04 (0.02, 0.05) <.01*
0.4 7.86 (5.47, 10.25) <.01* 7.02 (2.94, 11.11) <.01* 0.28 (0.02, 0.54) 0.04 0.60 (0.23, 0.98) <.01* 0.05 (0.03, 0.07) <.01*
0.4 (HT) 9.01 (5.67, 12.36) <.01* 6.88 (1.10, 12.66) 0.02 0.25 (−0.03, 0.53) 0.08 0.52 (0.06, 0.97) 0.03 0.03 (0.01, 0.05) <.01*

An asterisk indicates p<0.0125 for the comparison with the 15.8 mg/g group.