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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: J Clin Pharmacol. 2016 Aug 23;57(2):219–229. doi: 10.1002/jcph.796

Figure 4. Simulations of the metformin plasma concentrations at A) 850 mg bid; B) 1000 mg bid; C) 1350 mg bid for pediatric patients with estimated glomerular filtration rates of 90, 120 and 180 mL/min/1.73 m2, respectively.

Figure 4

The 2.5th (lower dotted line), 50th (solid dotted line) and 97.5th (upper dotted line) percentiles of the simulated concentrations are shown.