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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Connect Tissue Res. 2016 Jul 12;58(1):64–75. doi: 10.1080/03008207.2016.1211113

Figure 3. SAHA downregulates miR-9 expression in OA chondrocytes and in cultured OA cartilage explants.

Figure 3

(a) Chondrocytes or (b) cartilage explants were stimulated with IL-1β (2ng/ml; n=3) in the presence or absence of SAHA (1mM; n=5) for 16 hrs or 4 days. Total RNA was harvested and miR-9 expression was measured by TaqMan assay. Expression of RNU6B was used as a normalizing control. (*P <0.05; **P <0.005; paired student t-test).