Figure 3.
Polyene chain of retinylidene ligand is locked in a twisted conformation in the inverse agonist form. (a)–(h) Torsion angle distributions along the conjugated polyene chain from C7 to C15. Twisting of the polyene chain from planarity (torsion angle χ = 180°) is mainly confined to the C10–C11 and C12–C13 torsions to either side of the C11=C12 double bond.