Table 3. Linear Regression Analyses Using Each Neuropsychological Test Score and the Personality Assessment Inventory as the Outcome Variable in Separate Adjusted Models1.
Essential Tremor vs. Healthy Controls | Essential Tremor vs. Parkinson’s Disease | Parkinson’s disease vs. healthy controls | ||||
---|---|---|---|---|---|---|
β | p | β | p | β | p | |
Global cognitive performance | ||||||
Mini-Mental State Examination | 0.221 | 0.097 | –0.119 | 0.281 | 0.367 | 0.004 |
Executive function and attention | ||||||
Direct Digit Span subtest from the WAIS-III | 0.012 | 0.929 | –0.120 | 0.251 | 0.063 | 0.638 |
Indirect Digit Span subtest from the WAIS-III | 0.216 | 0.086 | –0.058 | 0.618 | 0.179 | 0.164 |
Coding-Digit Symbol subtest from the WAIS-III | 0.370 | <0.001 | 0.018 | 0.831 | 0.343 | <0.001 |
Similarities subtest from the WAIS-III | 0.285 | 0.013 | 0.029 | 0.734 | 0.208 | 0.054 |
Trail-making Test, B – A | –0.323 | 0.017 | 0.171 | 0.195 | –0.417 | 0.002 |
Stroop Color–Word Trial (interference effects) | 0.118 | 0.422 | –0.108 | 0.390 | 0.258 | 0.068 |
Wisconsin Card Sorting Test (errors) | 0.108 | 0.389 | 0.050 | 0.690 | 0.049 | 0.697 |
Wisconsin Card Sorting Test (perseverations) | 0.103 | 0.440 | 0.055 | 0.683 | –0.018 | 0.891 |
Tower of London (time of execution in seconds) | –0.180 | 0.137 | 0.079 | 0.519 | –0.266 | 0.043 |
Frontal Assessment Battery | 0.318 | 0.011 | –0.033 | 0.789 | 0.391 | 0.003 |
Visuospatial ability | ||||||
Benton Judgment of Line Orientation Test | 0.092 | 0.453 | –0.216 | 0.063 | 0.187 | 0.176 |
Hooper Visual Organization Test | 0.183 | 0.157 | –0.193 | 0.114 | 0.366 | 0.002 |
Verbal memory | ||||||
WMS-III Word List | ||||||
Learning | 0.170 | 0.177 | –0.079 | 0.472 | 0.176 | 0.154 |
Immediate recall | 0.265 | 0.044 | 0.135 | 0.247 | 0.038 | 0.783 |
Delayed recall | 0.279 | 0.026 | 0.065 | 0.576 | 0.174 | 0.187 |
Delayed recognition | 0.312 | 0.013 | 0.150 | 0.293 | 0.221 | 0.128 |
Visual memory | ||||||
Brief Visuospatial Memory Test-Revised | ||||||
Learning trials | 0.388 | 0.002 | 0.002 | 0.983 | 0.468 | <0.001 |
Delayed recall trial | 0.380 | 0.003 | 0.002 | 0.989 | 0.430 | <0.001 |
Recognition trial | 0.186 | 0.198 | –0.208 | 0.123 | 0.318 | 0.018 |
Language | ||||||
Boston Naming Test | 0.297 | 0.013 | –0.132 | 0.222 | 0.376 | 0.003 |
Category-cued Word Fluency | 0.079 | 0.534 | 0.029 | 0.780 | 0.116 | 0.336 |
Controlled Oral Word Association Test | 0.270 | 0.019 | 0.070 | 0.479 | 0.166 | 0.174 |
Personality and Psychopathology | ||||||
Personality Assessment Inventory | ||||||
Somatic concerns | –0.223 | 0.093 | –0.154 | 0.200 | –0.051 | 0.694 |
Anxiety | –0.230 | 0.033 | –0.220 | 0.064 | –0.022 | 0.874 |
Anxiety related disorders | –0.123 | 0.311 | –0.274 | 0.028 | 0.209 | 0.154 |
Depression | –0.309 | 0.003 | –0.134 | 0.186 | –0.057 | 0.604 |
Mania | –0.069 | 0.636 | –0.194 | 0.153 | 0.041 | 0.791 |
Paranoia | –0.114 | 0.413 | –0.196 | 0.147 | 0.174 | 0.248 |
Schizophrenia | –0.068 | 0.591 | –0.256 | 0.026 | 0.296 | 0.039 |
Borderline features | –0.073 | 0.559 | –0.341 | 0.008 | 0.284 | 0.049 |
Antisocial features | –0.230 | 0.081 | –0.086 | 0.516 | –0.116 | 0.405 |
Alcohol problems | –0.120 | 0.421 | –0.093 | 0.495 | 0.036 | 0.828 |
Drug problems | 0.199 | 0.179 | –0.082 | 0.578 | 0.299 | 0.044 |
Significant values are in bold font.
Adjusted for age, sex, years of education, medications that potentially affect cognitive function, total number of medications, and 17-item Hamilton Depression Rating Scale total score.