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. 2016 Dec 21;15:112–126. doi: 10.1016/j.ebiom.2016.12.009

Table 1.

Breakdown of patient classes recruited for this study.

Condition No. of samples Age range (yrs) Gender male (M), female (F) Clinical summary
Active TB 19 18–52 11M, 8F All 19 cases are sputum smear positive with grade 2 to 3. Chest X-ray is abnormal in all, 13 with bilateral and 6 with unilateral abnormality, with 1 to 6 zones, 6 show cavities and 13 show no cavities. Almost all patients show normal hematology
HC 15 30–60 8M, 7F All are sputum smear negative, chest X-rays appear normal, no clinical symptoms of TB and no known prior history of TB
LTB IGRA + ve 13 19–34 11M, 2F All are sputum smear negative, chest X-rays appear normal, no clinical symptoms of TB and no known prior history of TB



Condition No. of samples Age range (yrs) Gender CD4 cells/mm Viral load copies/ml Clinical summary
HIV 7 25–47 4M, 3F 16–28%; mean: 20.5% (not investigated in 2) 3.4 × 101 to 8.2 × 104 All patients are treatment-naive and show normal chest X-rays with no evidence of TB