Table 2. Clinical Fefatures of Ophthalmic Giant Cell Arteritis.
| African-Americana (n=32) | Caucasianb | Odds Ratio (95% CI) | P-valuec | |
|---|---|---|---|---|
| Systemic Symptomsd n=85 | ||||
| Fever | 2/19 (11%) | 12 (14%) | 0.72 (0.15, 3.50) | 1.00 |
| Weight loss | 10/25 (40%) | 29 (34%) | 1.29 (0.51, 3.22) | 0.59 |
| Malaise | 5/19 (26%) | 27 (32%) | 0.77 (0.25, 2.35) | 0.79 |
| Anorexia | 4/18 (22%) | 25 (29%) | 0.69 (0.21, 2.29) | 0.77 |
| Headache | 21/28 (75%) | 38 (45%) | 3.71 (1.43, 9.66) | <0.01 |
| Jaw claudication | 9/29 (31%) | 46 (54%) | 0.38 (0.16, 0.93) | 0.03 |
| Neck pain | 9/16 (56%) | 11 (13%) | 8.65 (2.68, 28.0) | <0.001 |
| Scalp tenderness | 7/29 (24%) | 15 (18%) | 1.48 (0.54, 4.11) | 0.44 |
| Myalgia | 3/18 (17%) | 12 (14%) | 1.22 (0.31, 4.84) | 0.72 |
| Anemia (Hgb<11 g/dl) | 10/29 (34%) | 12 (14%) | 3.20 (1.20, 8.53) | 0.02 |
| Ophthalmic Symptoms n=84 | ||||
| Amaurosis fugax | 5 (16%) | 26 (31%) | 0.42 (0.15, 1.21) | 0.16 |
| Acute vision loss | 25 (78%) | 82 (98%) | 0.09 (0.02, 0.45) | <0.001 |
| Diplopia (transient or permanent) | 4 (13%) | 5 (6%) | 2.29 (0.57, 9.12) | 0.25 |
| Eye pain | 9 (28%) | 7 (8%) | 4.36 (1.46, 13.0) | <0.01 |
| Ophthalmic Signs n=84 | ||||
| Anterior ischemic optic neuropathy | 20 (63%) | 68 (81%) | 0.39 (0.16, 0.96) | 0.04 |
| Central retinal artery occlusion | 4 (13%) | 12 (14%) | 0.87 (0.26, 2.92) | 1.00 |
| Posterior ischemic optic neuropathy | 2 (6%) | 6 (7%) | 0.88 (0.17, 4.59) | 1.00 |
a
Not all systemic symptom data was collected for all African-American patients.
b
Published cohort18 Individual headings indicate the number of patients.
c
Fisher's exact test when there are five or fewer patients with any race/characteristic combination, χ2-test otherwise.
d
Systemic symptoms data was not available for the single African-American patient, thus the Caucasian group includes the single African-American patient (n=85) for these comparisons.