Figure 1.

(a) Optical coherence tomography B-scan demonstrating subretinal hyperreflective material (SRHM—‘hyperreflective' space), subretinal fluid (SRF—‘hyporeflective' space), and pigment epithelial detachment (PED). (b) The clinically relevant boundaries—internal limiting membrane (ILM), outer border of photoreceptors, retinal pigment epithelium (RPE), inner and outer borders of SRHM, and the estimated normal location of the RPE layer are drawn using 3D-OCTOR software. (c) 3D-OCTOR then computes the volumes of the spaces (retina, SRHM, SRF, and PED) defined by these boundaries.